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PubMed COVID-19 Clinical Care

42621 - 42630 of 44979 results found

Application of estimand framework in ICH E9 (R1) to safety evaluation

Date
Thursday, March 23, 2023 - 4:00 AM
Description
Defining the right question of interest is important to a clinical study. ICH E9 (R1) introduces the framework of an estimand and its five attributes, which provide a basis for connecting different components of a study with its clinical questions

Liver and Renal Injury with Remdesivir Treatment in SARS-CoV-2 Patients

Date
Thursday, March 23, 2023 - 4:00 AM
Description
CONCLUSION: Only three patients developed adverse effects resulting in stopping of Remdesivir, however these were reversible on stopping the drug. Therefore, Remdesivir is a relatively safe drug and well tolerated in SARS-CoV-2 patients.

Nanotechnologically Relevant Aspects of COVID-19 Vaccines

Date
Thursday, March 23, 2023 - 4:00 AM
Description
The COVID-19 pandemic has affected several facets of human existence globally. To counter the spread of the virus, several vaccines have been developed and administered worldwide, using various technologies. Due to the need for the mRNA to be safely