PubMed COVID-19 Clinical Care

Cases of cryptococcosis have been reported in patients with COVID-19. The majority are in patients with severe symptoms or who received immunosuppressants. However, there is still no clear association between COVID-19 and cryptococcosis. We report

Air pollution affects climate change, food production, traffic safety, and human health. In this paper, we analyze the changes in air quality index (AQI) and concentrations of six air pollutants in Jinan during 2014-2021. The results indicate that

Context: The COVID-19 pandemic and associated public health measures have substantially increased stress on families, including financial stress. Objective: To explore the association between familial financial stress and child socioemotional and

The COVID-19 pandemic has led to increased patient volumes, staff shortages, and limited resources in emergency departments (EDs), resulting in the rapid acceleration of telemedicine in emergency medicine. The Virtual First (VF) program connects

The study of the role of cytokines in various pathological conditions of the body is a topical area in modern biomedicine. Understanding the physiological roles played by cytokines will aid in finding applications for them as pharmacological agents

STAT2 is a transcription factor activated by type I and III interferons. We report 23 patients with loss of function variants causing autosomal recessive (AR), complete STAT2 deficiency. Both cells transfected with mutant STAT2 alleles and the

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CONCLUSION: Combination therapy including two antivirals (mainly remdesivir and nirmatrelvir/ritonavir) and Mabs was associated with high rate of virological and clinical response in immunocompromised patients with prolonged/relapsed COVID-19.

COVID-19 has significantly affected hospital infection prevention and control (IPC) practices, especially in intensive care units (ICUs). This frequently caused dissemination of multidrug-resistant organisms (MDROs), including carbapenem-resistant

Antiviral compounds targeting cellular metabolism are part of the therapeutic arsenal to control the spread of virus infection, either as sole treatment or in combination with direct-acting antivirals (DAA) or vaccines. Here, we describe the effect