PubMed COVID-19 Clinical Care

Nirmatrelvir is a potent and selective SARS-CoV-2 main protease inhibitor. Nirmatrelvir co-packaged with ritonavir (as PAXLOVID^(TM) ) received FDA Emergency Use Authorization (EUA) on 22 Dec 2021 as an oral treatment for COVID-19 and subsequent NDA

CONCLUSION: Concurrent COVID-19 infection is associated with a significant increase in morbidity and mortality in patients with GP and GN BSIs. Patients with S. aureus BSIs with COVID-19 are more likely to develop shock and respiratory failure and

Remdesivir 1 is an phosphoramidate prodrug that releases the monophosphate of nucleoside GS-441524 (2) into lung cells, thereby forming the bioactive triphosphate 2-NTP. 2-NTP, an analog of ATP, inhibits the SARS-CoV-2 RNA-dependent RNA polymerase

CONCLUSIONS: Baricitinib use was associated with better WHO-CPS scores at day 14 and day 7 compared with tocilizumab in a cohort of critically ill patients with COVID-19. The odds of having a one unit increase in WHO-CPS score at day 14 was 71%

No abstract

CONCLUSION: The efficacy and quality of life of the Zilongjin tablets combined conventional chemotherapy for NSCLC were significantly better than chemotherapy alone, alleviating various adverse effects. At the same time, the Zilongjin tablets may

The concept of standardized patients (SPs) was first introduced in the 1960s by Dr. Howard Barrows of the University of Southern California and has been applied in medical school education since that time. This practice has allowed medical students

[This retracts the article DOI: 10.1155/2022/4279346.].

Three and a half years into the COVID-19 pandemic, the nature and durability of protection against SARS-CoV-2 still remains unclear. Current COVID-19 mRNA vaccines have been shown to provide minimal protection against infection with XBB variants but

Ursodeoxycholic acid (UDCA), an off-patent drug used to treat liver disease, is able to block SARS-CoV-2 entry into the cells downregulating ACE2 expression, a promising strategy to protect against infection. In this light, John et al. have recently